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What (who) is 3β-Hydroxysteroid dehydrogenase - definition
3β-Hydroxysteroid dehydrogenase
CLASS OF ENZYMES
3Beta Hydroxysteroid dehydrogenase; 3β-HSD; 3b-hydroxy-D5-steroid dehydrogenase; Progesterone reductase; 3-beta-hydroxysteroid dehydrogenase; 3beta-hydroxy-Delta5-steroid dehydrogenase; 3b-HSD; Delta 4-5 isomerase; 3 beta-hydroxysteroid dehydrogenase; 3β-hydroxysteroid dehydrogenase; 3βHSD II; 3-beta HSD; 3-β-hydroxysteroid dehydrogenase; 3-β-Hydroxysteroid dehydrogenase; 3-beta-HSD; 3beta-hydroxysteroid dehydrogenase; EC 1.1.1.145; 3beta-hydroxy-Delta5-steroid:NAD+ 3-oxidoreductase; 3β-hydroxysteroid dehydrogenase/Δ-5-4 isomerase; Delta 5-4 isomerase; 3beta-Hydroxysteroid dehydrogenase; 3β-Hydroxysteroid dehydrogenases; 3β-hydroxy-Δ5-C27-steroid oxidoreductase; 3β-Hydroxysteroid dehydrogenase inhibitor; 3β-Hydroxysteroid dehydrogenase inhibitors; 3β-hydroxysteroid dehydrogenase inhibitors; 3β-hydroxysteroid dehydrogenase inhibitor; 3β-HSD inhibitor; 3β-HSD inhibitors; 3B-HSD inhibitors; 3B-HSD inhibitor; 3B-hydroxysteroid dehydrogenase inhibitor; 3B-hydroxysteroid dehydrogenase inhibitors; 3B-Hydroxysteroid dehydrogenase inhibitors; 3B-Hydroxysteroid dehydrogenase inhibitor; 3beta-Hydroxysteroid dehydrogenase inhibitor; 3beta-Hydroxysteroid dehydrogenase inhibitors; 3beta-hydroxysteroid dehydrogenase inhibitors; 3beta-hydroxysteroid dehydrogenase inhibitor; 3beta-HSD inhibitor; 3beta-HSD inhibitors; 3-beta-HSD inhibitors; 3-beta-HSD inhibitor; 3-beta-hydroxysteroid dehydrogenase inhibitor; 3-beta-hydroxysteroid dehydrogenase inhibitors; 3-beta-Hydroxysteroid dehydrogenase inhibitors; 3-beta-Hydroxysteroid dehydrogenase inhibitor
3β-Hydroxysteroid dehydrogenase/Δ5-4 isomerase (3β-HSD) () is an enzyme that catalyzes the biosynthesis of the steroid progesterone from pregnenolone, 17α-hydroxyprogesterone from 17α-hydroxypregnenolone, and androstenedione from dehydroepiandrosterone (DHEA) in the adrenal gland. It is the only enzyme in the adrenal pathway of corticosteroid synthesis that is not a member of the cytochrome P450 family.
Hydroxysteroid dehydrogenase
![[[Steroidogenesis]].](https://commons.wikimedia.org/wiki/Special:FilePath/Steroidogenesis.svg?width=200 "[[Steroidogenesis]].")
CLASS OF OXIDOREDUCTASE ENZYMES HAT CATALYZE THE DEHYDROGENATION OF HYDROXYSTEROIDS
3-alpha hydroxysteroid dehydrogenase; Hydroxysteroid dehydrogenases; Hydrosteroid dehydrogenase; Ketosteroid reductase; Ketosteroid reductases
Hydroxysteroid dehydrogenases (HSDs) are a group of alcohol oxidoreductases that catalyze the dehydrogenation of hydroxysteroids. These enzymes also catalyze the reverse reaction, acting as ketosteroid reductases (KSRs).
17β-Hydroxysteroid dehydrogenase
CLASS OF ENZYMES
17-beta-hydroxysteroid dehydrogenase isozyme 3; 17BHSD3; 3(or 17)b-hydroxysteroid dehydrogenase; 17β-hydroxysteroid dehydrogenase; 17b-hydroxysteroid dehydrogenase; 17b-Hydroxysteroid dehydrogenase; 17bHydroxysteroid-Dehydrogenase; 17B-HSD; EC 1.1.1.51; 3(or 17)beta-hydroxysteroid:NAD(P)+ oxidoreductase; 17Beta Hydroxysteroid dehydrogenase; 17β hydroxysteroid dehydrogenase; 17-ketosteroid reductase; 17-Ketosteroid reductase; 17-Ketosteroid reductases; 17-ketosteroid reductases; 17-ketosteroid oxidoreductases; 17-ketosteroid oxidoreductase; 17-Ketosteroid oxidoreductase; 17-Ketosteroid oxidoreductases; 17-Ketoreductases; 17-Ketoreductase; 17-ketoreductase; 17-ketoreductases; HSD17B; 17β-HSD; 17β-Hydroxysteroid dehydrogenases; 17β-hydroxysteroid dehydrogenases; 17β-HSDs; HSD17Bs; HSD17B*; 17-KSR; 17-KSRs; 17β-Hydroxysteroid dehydrogenase inhibitor; 17β-Hydroxysteroid dehydrogenase inhibitors; 17β-hydroxysteroid dehydrogenase inhibitors; 17β-hydroxysteroid dehydrogenase inhibitor; 17β-HSD inhibitor; 17β-HSD inhibitors; 17beta-HSD inhibitor; 17beta-HSD inhibitors; 17beta-hydroxysteroid dehydrogenase inhibitors; 17beta-hydroxysteroid dehydrogenase inhibitor; 17beta-Hydroxysteroid dehydrogenase inhibitor; 17beta-Hydroxysteroid dehydrogenase inhibitors; 17B-Hydroxysteroid dehydrogenase inhibitors; 17B-Hydroxysteroid dehydrogenase inhibitor; 17B-hydroxysteroid dehydrogenase inhibitor; 17B-hydroxysteroid dehydrogenase inhibitors; 17B-HSD inhibitor; 17B-HSD inhibitors; 17-beta-HSD inhibitors; 17-beta-HSD inhibitor; 17-beta-hydroxysteroid dehydrogenase inhibitor; 17-beta-hydroxysteroid dehydrogenase inhibitors; 17-beta-Hydroxysteroid dehydrogenase inhibitors; 17-beta-Hydroxysteroid dehydrogenase inhibitor
17β-Hydroxysteroid dehydrogenases (17β-HSD, HSD17B) (), also 17-ketosteroid reductases (17-KSR), are a group of alcohol oxidoreductases which catalyze the reduction of 17-ketosteroids and the dehydrogenation of 17β-hydroxysteroids in steroidogenesis and steroid metabolism. This includes interconversion of DHEA and androstenediol, androstenedione and testosterone, and estrone and estradiol.
